Psychiatric drug development in Japan.
نویسندگان
چکیده
While psychiatrists in the West are reaping the benefits of the surge in drug development during the past 10 years, psychiatrists in Japan are currently treating mental illness with a psychopharmacologic armamentarium that was considered state of the art in the United States in the early 1980s. None of the new generation antidepressants, antianxiety agents, or antipsychotics that have made great changes in the way psychiatry is practiced in the West have yet been approved by the Japanese Ministry of Health and Welfare (MHW). Considering Japan's cutting edge position in most other areas of technology, this lag seems a bit surprising.
منابع مشابه
Pathogenesis of Atopic Dermatitis: Current Paradigm
Atopic dermatitis (AD) is characterized by skin inflammation, barrier dysfunction and chronic pruritus. In this review, recent advances in the pathogenesis of AD are summarized. Clinical efficacy of the anti-IL-4 receptor antibody dupilumab implies that type 2 cytokines IL-4 and IL-13 have pivotal roles in atopic inflammation. The expression of IL-4 and IL-13 as well as type 2 chemokines such a...
متن کاملThe epidemiology of adverse drug events and medication errors among psychiatric inpatients in Japan: the JADE study
BACKGROUND Knowledge of the epidemiology of adverse drug events (ADEs) and medication errors in psychiatric inpatients is limited outside Western countries. The nature of ADEs and medication errors are important for improving the quality of care worldwide; therefore, we conducted the Japan Adverse Drug Events Study, a series of cohort studies at several settings in Japan. METHODS This report ...
متن کاملA Study of Psychotropic Drugs Being Prescribed to the Patients Attending the Psychiatric Outpatient Department in a Tertiary Care Hospital
BACKGROUND & PURPOSE: Drug utilization research evaluates the appropriateness of the prescriptions which is important in clinical practice. Psychotropic polypharmacy is a major problem in psychiatric practice, which can lead to the development of adverse effects of those drugs in patients. Therefore, this study was carried out to evaluate the utilization of psychotropic drugs being prescribed f...
متن کاملRecent changes in the clinical features of patients with new psychoactive-substances-related disorders in Japan: Comparison of the Nationwide Mental Hospital Surveys on Drug-related Psychiatric Disorders
Toshihiko Matsumoto, MD, PhD,* Hisateru Tachimori, PhD, Ayumi Takano, MS, Yuko Tanibuchi, MD, PhD, Daisuke Funada, MD and Kiyoshi Wada, MD, PhD Departments of Drug Dependence Research, Mental Health Administration, National Institute of Mental Health, Department of Psychiatry, Center Hospital, National Center of Neurology and Psychiatry, Department of Psychiatric Nursing, Graduate School of Med...
متن کاملMorphology control of clay-mineral particles as supports for metallocene catalysts in propylene polymerization
Spray dry granulation of clay minerals was studied to obtain clay mineral base support material for metallocene supported olefin polymerization catalysts. The morphology of the granules was strongly influenced by the nature of the clay mineral itself. Because of swelling characteristics of montmorillonite, its water dispersion was highly viscous even in the low slurry concentration (< 4 wt %). ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید
ثبت ناماگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید
ورودعنوان ژورنال:
- Science
دوره 273 5273 شماره
صفحات -
تاریخ انتشار 1996